3 Year Fixed Term Contract
The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future.
The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease. Our Science Strategy seeks to focus the Franklin’s research and unite our researchers around our Technology Innovation Challenges and Life Science Challenges.
The Role | Research Assistant
We are seeking a highly motivated Research Assistant to support cutting-edge research in cell-cell interaction in epithelia. The role will focus on the development and genetic modification of human gut organoid and cell models, including the generation of fluorescently tagged proteins and disease-relevant phenotypes. The role will involve apply molecular biology techniques including DNA cloning, qPCR, and sequencing, CRISPR/Cas9 genome editing, advanced 2D and 3D cell culture, and fluorescence imaging techniques including super resolution. The post-holder will handle human tissue samples in compliance with HTA regulations and prepare growth factors for organoid maintenance.
The successful candidate will support a collaborative, multidisciplinary research environment.
Key Responsibilities | Research Assistant
As a Research Assistant at the Franklin, you will become an integral part of the research team, supporting the work of scientists, by ensuring the smooth running of the labs. You will manage technologies and reagents and provide services to support the work of students and scientists of all levels. You may also be asked to undertake well defined experimental protocols in a supervised fashion.
You will also:
This job description set outs the skills and experience we believe are needed to be able to do this job but, research also tells us women are much more likely than men to take this list of requirements as absolute and self-select out of the process. If you think you can deliver this role then we want to hear from you, regardless of the boxes you did not tick.
In return we offer:
The Franklin’s underlying aim is to produce the best science for research today, and this means resolutely embracing a diverse team, who have a wide range of experiences, skills and knowledge to push forward on the innovative work our institution delivers. Both our work and our institution are better for it.
We are committed to creating an inclusive environment where every applicant has an equal opportunity to showcase their talents and abilities. This includes making adjustments for candidates with specific needs. Please contact us to discuss your requirements confidentially.
At the Rosalind Franklin Institute we also welcome applications from all around the world!
To be considered for this role, please submit a CV and cover letter explaining why you think you are the right person for this job. Please include information about your education and work experience.
Closing date: The closing date for applications is 23:59 on Sunday 15th March 2026
The Rosalind Franklin Institute is a national interdisciplinary research centre, funded by the UK government through UK Research and Innovation (UKRI). We are dedicated to creating new disruptive technologies which will allow us to see the biological world in new ways - from picometre-scale atoms to centimetre-scale tumours. These technological advances will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease.
The Franklin operates from a purpose-built research facility on the Harwell Science and Innovation Campus near Didcot, a unique community of government, academia and industry working to accelerate progress on key issues. The 700-acre campus is steeped in world-firsts, and technology and research are at the heart of everything Harwell does.
Our building houses both specialist laboratories, research scientists and operational staff within a state-of-the art facility designed to inspire our people in their work and create a welcoming hub for our collaborations and visitors. Our research values of adventure, novelty, engagement, and utility are drawn on and exemplified by the Franklin team through our collaborations with universities and industrial partners, both in the UK and internationally.
The Franklin’s underlying aim is to produce the best science for research today, and this means resolutely embracing a diverse team, who have a wide range of experiences, skills and knowledge to push forward on the innovative work our institution delivers.

At the Franklin we are all about the science, but we can’t do great science without great people. Creating opportunities for our people to fulfil their potential and feel proud of their work is important to us. This goes for all our teams so whether you are a technician, scientist or one of the professionals which make up our operations team, everyone at the Franklin has a part to play in making us a success.
Our approach to working is collaborative, welcoming, and encourages diversity in all its forms. We are committed to creating an inclusive environment where everyone has an equal opportunity to showcase their talents and abilities. This includes making adjustments for candidates with specific needs.

We have a fantastic benefits package, which includes opportunities for continuous learning, a generous annual leave entitlement, flexible working to help you maintain a healthy work-life balance and other wellbeing support.
The Rosalind Franklin Institute is committed to fostering a diverse, inclusive, and equitable workplace. Our aim is simply to reflect the world we live in, having a diverse workforce which is representative of the rich cultures, experiences, backgrounds and skills that the UK and the world has to offer, and ensuring that we build an environment of mutual support and respect for everyone. Our people create a vibrant scientific community. Our culture is forward thinking and progressive bridging the gap between academia and industry, building strong collaborations and networks to enhance career opportunities. We encourage personal development and growth, creating opportunities to learn leadership skills, build personal networks and be supported by coaches and mentors.
As an organisation we appreciate that our people are one of our biggest strengths. We are committed to supporting your learning and development, helping you gain the skills you need to succeed in your role. Regardless of your level of experience and your role, we can assist you with building your expertise, experience and professional qualifications at key career stages.

We have a brand new hub building with world-class laboratory facilities with open plan social areas for people to come together. It really is an amazing place to work and collaborate.
We are located on the Harwell Science and Innovation campus which has an array of sports and recreation facilities open for all staff as well as a subsidised canteen and other food outlets. Which creates a great campus feel when working here and access to many additional networks, groups and events.